Chem Pharm Bull 58(8):1033–1036īacon CW, White JF (2000) Microbial endophytes.

Appl Microbiol Biotechnol 90:1829–1845Īrunpanichlert J, Rukachaisirikul V, Sukpondma Y, Phongpaichit S, Tewtrakul S, Rungjindamai N, Sakayaroj J (2010) Azaphilone and isocoumarin derivatives from the endophytic fungus Penicillium sclerotiorum PSU-A13. KeywordsĪly AH, Debbab A, Proksch P (2011) Fungal endophytes: unique plant inhabitants with great promises. This chapter reviews these important non-analogous bioactive compounds produced by endophytic fungi. However, apart from producing host-related compounds, endophytic fungi also produce several important non-analogous compounds like altenusin, beauvericin, and phomoxanthones which exhibit diverse biological activities. Over the last two decades, endophytic fungi have gained much attention due to their immaculate ability in synthesizing host-related bioactive compounds like taxol, camptothecin, podophyllotoxin, vincristine, and vinblastine. Endophytic fungi are microbial factories inside the plant which produces novel and structurally diverse bioactive compounds that can be directly or indirectly used as potent drug for combating major global diseases. Plant-microbe interaction in an unexposed biological niche plays an important role in discovering new chemistries for pharmaceutical and industrial applications. However, seldom has been thought of niches which are hidden, symbiotic, and neutral in nature.

Exploration of microorganism from different niches in search of novel compounds has been a mainstay in pharmaceutical as well as agrochemical industries. Microorganisms have been in service to mankind by virtue of their secondary metabolites which have diverse applications in the areas of food, health, and agriculture.

Novel trove